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Severe suffering

Severe suffering

General guidance

  • Avoiding mortality in animal research and testing (2019)
     
  • The RSPCA focus on severe suffering project (2016)
     
  • A 'road map' toward ending severe suffering of animals used in research and testing (2014)
     
  • Discussion paper: Reducing severe suffering (2013)
     
  • Refinement - Lessons from the 2012 Olympics (2013)
     
  • Focus on Severe Suffering Infographic (PDF 120KB) (2020)


Specific procedures

  • Refining rodent models of spinal cord injury (2020)
     
  • Applying refinement to the use of mice and rats in rheumatoid arthritis research (2015)
     
  • Refinement of animal models of sepsis and septic shock (2015, not open access)
     
  • Reducing suffering in experimental autoimmune encephalomyelitis (EAE) (2013, not open access)
     
  • Reducing suffering in animal models and procedures involving seizures, convulsions and epilepsy (2013, not open access)
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