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    Severe suffering

    Severe suffering

    General guidance

    • Avoiding mortality in animal research and testing (2019)
       
    • The RSPCA focus on severe suffering project (2016)
       
    • A 'road map' toward ending severe suffering of animals used in research and testing (2014)
       
    • Discussion paper: Reducing severe suffering (2013)
       
    • Refinement - Lessons from the 2012 Olympics (2013)
       
    • Focus on Severe Suffering Infographic (2020)


    Specific procedures

    • Refining rodent models of spinal cord injury (2020)
       
    • Applying refinement to the use of mice and rats in rheumatoid arthritis research (2015)
       
    • Refinement of animal models of sepsis and septic shock (2015, not open access)
       
    • Reducing suffering in experimental autoimmune encephalomyelitis (EAE) (2013, not open access)
       
    • Reducing suffering in animal models and procedures involving seizures, convulsions and epilepsy (2013, not open access)

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